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Changing focus in type 2 diabetes from glucose to cardiovascular risk management

Changing focus in type 2 diabetes from glucose to cardiovascular risk management

with a focus on SGLT2-inhibitors

Bernard Charbonnel

 Professor of Endocrinology and Metabolic Diseases

 University of Nantes, France

Changing focus in type 2 diabetes

Two main questions

  1. Is Type 2 Diabetes more a cardio-vascular disease than a metabolic disease?

     in other terms, is the management of

type 2 Diabetes driven

     by blood glucose control

     or by cardio-vascular events prevention?

 

  1. Which lessons from

     the outcome studies?

 

Of course, Diabetes is a cardio-vascular disease

50 % of the diabetic patients die from an heart attack

2/3 of patients in intensive care cardiology units have some kind of glucose intolerance

High prevalence of strokes in diabetic patients

Heart Failure is becoming the most frequent and serious cardio-vascular complication of Diabetes